Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach

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Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.

BACKGROUND The epididymal epithelium secretes membranous vesicles, called epididymosomes, with which a complex mixture of proteins is associated. These vesicles transfer to spermatozoa selected proteins involved in sperm maturation. Epididymosomes in the human excurrent duct have been described, but their protein composition and possible functions are unknown. METHODS AND RESULTS Epididymosom...

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Vasectomy reversal.

A small personal series of vasovasostomies and a review of the literature on this subject are presented. The importance is stressed of good counselling before vasectomy is undertaken in the first place.

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Vasectomy reversal

Vasectomy is an elective surgical sterilization procedure for men that is intended to obstruct or remove a portion of both vas deferens, thereby preventing sperm from moving from the testes to the ejaculatory ducts. Although intended for permanent sterilization, vasectomy can be reversed in most men seeking to restore their fertility due to a change in marital status or reproductive goals. The ...

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Vasectomy reversal for post-vasectomy pain syndrome

Post-vasectomy pain syndrome (PVPS) is a rare, but devastating outcome following vasectomy. Given the widespread utilization of vasectomy for permanent contraception, with more than 500,000 procedures performed annually in the United States, it can be a significant challenge for both patients and providers. Vasectomy reversal is a surgical option for men who fail conservative or medical managem...

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Vasectomy reversal in humans

Vasectomy is the most common urological procedure in the United States with 18% of men having a vasectomy before age 45. A significant proportion of vasectomized men ultimately request vasectomy reversal, usually due to divorce and/or remarriage. Vasectomy reversal is a commonly practiced but technically demanding microsurgical procedure that restores patency of the male excurrent ductal system...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2008

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/den181